厦门大学生命科学学院导师介绍：徐庆妍

  徐庆妍  XU Qingyan, Ph.D.
  副教授硕士生导师
  电  话:+86-592-2180328
  E-mail: xuqingyan@yahoo.com
  1992年,华西医科大学药学院（今四川大学华西药学院）,学士学位；
  1995年,华西医科大学药学院（今四川大学华西药学院）天然药化专业,硕士学位；
  2004年,厦门大学,理学博士学位；
  2006年至2007年,法国斯特拉斯堡市路易－巴斯德大学药学院，博士后；
  1995年至今，厦门大学生命科学学院，助教、讲师、副教授。
  1992, B. Sc.  West China University of Medical Science
  1995, M. Sc.  West China University of Medical Science
  2004, Ph. D.  Xiamen University
  2006-2007, Postdoctoral Fellow, Louis-Pasteur University, Strasbourg, France
  1995-present, Assistant Professor, Associate Professor, School of Life Science, Xiamen University
  研究领域（Research Area）
  微生物药物学。从事与微生物活性代谢产物相关的研究。除抗菌、抗肿瘤活性外，目前主要从事抑制肿瘤坏死因子-α （TNF-α）活性的小分子化合物的研究，希望可以找到阻断TNF-α导致细胞坏死的信号通路的药物。
  Microbial Pharmacology. The main research area lies in Microbial Pharmacology. More than antibacterial and antitumor activities, we focus on the research of compounds with anti-TNF-α activity. We hope to find inhibitors that block the necrosis signaling pathway of TNF-α from microorganisms.
  代表性论文（Selected Publications）
  1.     Liu J L., Hu Z Y., Huang Y J., Zheng Z H, Xu Q Y*.  Aspochalasin U, a moderate TNF-α inhibitor from Aspergillus sp[J]. Journal of Antibiotics. 2012, 65 : 49-52.
  2.     Liu J L, Hu Z Y, Xu Q Y*. 3 '-(3-Hydroxyphenyl)-4-methylspiro benzo e 1,4 diazepine-3,2 '-oxirane -2,5(1H, 4H)-dione[J]. Acta Crystallographica Section E - Structure Reports Online, 2011, 67: O1670 - U1532.
  3.     Zimmermann M, Atmanene C, Xu Q Y, Fouillen L, Van Dorsselaer A, Bonnet D, Marsol C, Hibert M, Sanglier-Cianferani S, Pigault C, McNamara LK, Watterson DM, Haiech J*, Kilhoffer MC. Homodimerization of the Death-Associated Protein Kinase Catalytic Domain: Development of a New Small Molecule Fluorescent Reporter[J]. PLoS ONE, 2010, 5(11). E14120.
  4.     Zhan Y Y, Du X P, Chen H Z, Liu J J, Zhao B X, Huang D H, Li G D, Xu Q Y, Zhang M Q, Weimer B C, Chen D, Cheng Z, Zhang L R, Li Q X, Li S W, Zheng Z H, Song S Y, Huang Y J, Ye Z Y, Su W J, Lin S C, Shen Y M, Wu Q*. Cytosporone B is an agonist for nuclear orphan receptor Nur77 [J]. Nature Chemical Biology, 2008, 4(9):548-556.
  5.     Xu Z, Xu Q Y, Zheng Z H, Huang Y J*. Kribbella amoyensis sp. nov., isolated from the rhizosphere soil of a pharmaceutical plant, Typhonium giganteum Engl [J]. International Journal of Systematic and Evolutionary Microbiology, 2011. PMID: 21705443.