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上海交通大学内科学专业导师介绍:吴凌云

作者:聚创交大考研网-小黑老师 点击量: 1297 发布时间: 2015-07-09 18:13 【微信号:13306030226】


  
  基本信息
  导师姓名:吴凌云
  性别:女
  专业名称:内科学
  专业代码:100201
  培养单位:附属第六人民医院
  专业领域:血液病
  导师类型:硕士生导师
  邮箱地址:lincy2032@yahoo.com.cn

  研究方向
  骨髓增生异常综合征发病机制及诊治

  社会任职
  中华医学会上海市血液学分会委员

  科研项目

项目编号 项目名称 课题来源 起止年月 批准经费 承担职责
2ZR1422400 核糖体蛋白RPL23通过Miz1/c-Myc分子途径参RPL23在骨髓增生异常综合征发病中的作用 上海市自然科学基金 2013-01~2015-12 10万元  课题负责人
81200346 核糖体蛋白RPL23通过Miz1/c-Myc分子途径参与骨髓增生异常综合征发病的机制研究 国家自然科学基金 2013-01~2015-12 23万元  课题负责人

  学术论文

作者 论文标题 期刊名 出版年 卷期页码
张耀,宋陆茜,,常春康,李晓   p15INK4B甲基化与骨髓增生异常综合征患者预后及地西他滨疗效的关系  中华血液学杂志  2013  34(3) :237-241 
Zhang X, Chang C, Zhao Y,, Zhang Z, Li X.   The effect of the combination of bisphosphonates and conventional chemotherapy on bone metabolic markers in multiple myeloma patients.  Hematology  2012  17(5):255-60. 
, Li X, Xu F, Chang C, He Q, Zhang Z, Zhang Y.   Over-expression of RPL23 in myelodysplastic syndromes is associated with apoptosis resistance of CD34(+) cells and predicts poor prognosis and distinct response to CHG chemotherapy or decitabine.  Ann Hematol.  2012  91 (10):1547-1554 
Xu F,, He Q, Zhang Z, Chang C, Li X.  Immunophenotypic analysis of erythroid dysplasia and its diagnostic application in myelodysplastic syndromes.  Intern Med J  2012  42(4):401-11. 
Xu F, Yang R,, He Q, Zhang Z, Zhang Q, Yang Y, Guo J, Chang C, Li X.   Overexpression of BMI1 confers clonal cells resistance to apoptosis and contributes to adverse prognosis in myelodysplastic syndrome.  Cancer Lett.  2012  317(1):33-40 
Xiao L, Qi Z, Qiusheng C, Li X, Luxi S, The use of selective immunosuppressive therapy on myelodysplastic syndromes in targeted populations results in good response rates and avoids treatment-related disease progression.   Am J Hematol.  2012  87(1):26-31. 
Yang Y, Zhang Q, Xu F,, He Q, Li X.   Tumor suppressor gene BLU is frequently downregulated by promoter hypermethylation in myelodysplastic syndrome.  J Cancer Res Clin Oncol.  2012  138(5):729-37 
Zhang Y,, et al.  Low RPS14 gene expression is accompanied by p53-independent apoptosis in MDS patients with 5q- aberrations.  HealthMED  2012  6(7):2456-2463 
Xu F, Li X,, Zhang Q, Yang R, Yang Y, Zhang Z, He Q, Chang C.   Overexpression of the EZH2, RING1 and BMI1 genes is common in myelodysplastic syndromes: relation to adverse epigenetic alteration and poor prognostic scoring.   Ann Hematol.  2011  90(6):643-53 
, Li X, Su J, He Q, Zhang X, Chang C, Pu Q.   Efficacy and safety of CHG regimen (low-dose cytarabine, homoharringtonine with G-CSF priming) as induction chemotherapy for elderly patients with high-risk MDS or AML transformed from MDS.  J Cancer Res Clin Oncol  2011  137(10):1563-9. 
Zheng Z, Feng X, Xiao L, Qianqiao Z, Qi H, Removal of autologous activated CD4-positive T lymphocytes also results in increased colony-forming units in patients with low and intermediate-1 risk myelodysplastic syndromes.   Eur J Haematol.  2011  86(1):47-56. 
Li X, Xu F, He Q,, Zhang Z, Chang C.  Comparison of immunological abnormalities of lymphocytes in bone marrow in myelodysplastic syndrome (MDS) and aplastic anemia (AA).  Intern Med  2010  49(14):1349-55. 
Xu F, Li X,, He Q, Zhang Z, Chang C.  Flow cytometric scoring system (FCMSS) assisted diagnosis of myelodysplastic syndromes (MDS) and the biological significance of FCMSS-based immunophenotypes.  Br J Haematol  2010  149(4):587-97 
, Li X, Su J, Chang C, He Q, Zhang X, Xu L, Song L, Pu Q.   Effect of low-dose cytarabine, homoharringtonine and granulocyte colony-stimulating factor priming regimen on patients with advanced myelodysplastic syndrome or acute myeloid leukemia transformed from myelodysplastic syndrome.   Leuk Lymphoma  2009  50(9):1461-7 

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